研究一种与表面结合的亲和结合的稀土元素,该源自兰莫杜林EF-Hand Loop I的EF-Hand Loop I
Geeta Verma1, Jacob Hostert1, Alex A Summerville1
1Department of Chemical and Biomolecular Engineering, Case Western Reserve University, Cleveland, Ohio 44106, United States.
ACS applied materials & interfaces
|March 25, 2024
概括
模仿兰莫杜林的生物灵感对稀土元素 (REEs) 具有很高的选择性. 固定化保持强烈的REE结合亲和力,为从废物流中回收REE提供可持续的解决方案.
科学领域:
- 生物启发材料科学 生物启发材料科学
- 用于资源回收的生物技术.
- 稀土元素的分离 稀土元素的分离
背景情况:
- 生物启发策略提供从废物中可持续和选择性回收稀土元素 (REEs).
- 兰莫杜林蛋白具有很高的REE选择性,但更简单的仿真物对于实际应用是可取的.
- 对于先进的分离技术来说,对固体基板上的兰莫杜林衍生的固定至关重要,但仍未得到充分探索.
研究的目的:
- 设计和研究兰莫杜林衍生 (LanM1和编码LanM1) 的REE结合亲和力.
- 为了评估固定LanM1在固体表面的性能,以捕获REE.
- 为了证明表面结合的LanM1在REE与溶液分离中的实际实用性.
主要方法:
- 循环二元化 (CD),核磁共振 (NMR),分子动力学 (MD) 和异热定位热量计 (ITC) 用于基于溶液的结合特性.
- 石英晶体微平衡与消散 (QCM-D) 以评估在黄金表面上的固定性能.
- 使用Arsenazo III和UV-Vis光谱光度测试对金纳米粒子 (GNPs) 的REE捕获实验进行色度测量染料位移测定.
主要成果:
- 在溶液和固定状态下,LanM1表现出比混合的LanM1更强的REE结合亲和力.
- 固定的LanM1对REEs (Ce(III),Nd(III),Eu(III),Y(III) 保持了很高的亲和力,对竞争对手离子 (Ca(II),Cu(II)) 没有亲和力.
- 支持黄金纳米粒子的LanM1实现了目标REEs的和吸附能力约为3.5μmolREE/g.
结论:
- 在固体基板上固定时,兰莫杜林衍生 (LanM1) 有效地结合稀土元素.
- 表面的LanM1提供了可再生能源的选择性和高亲和度捕获,证明了废物流回收的潜力.
- 这项研究验证了生物灵感的使用,用于开发先进的REE分离技术.
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