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糖精嵌入的脂质载体用于DNA传递

Yinan Zhao1, Wanting Ma1, Kexin Tian2

  • 1Key Laboratory of Biotechnology and Bioresources Utilization of Ministry of Education, College of Life Sciences, Dalian Minzu University, Dalian 116600, China.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
|March 25, 2024
PubMed
概括

糖精 (SEs) 通过改善脂质体-DNA相互作用来增强基因传递. 糖劳拉酸 (COL-6) 显示出最佳的DNA结合和稳定性,从而达到最高的输送效率.

关键词:
提供DNA DNA交付互动 互动 互动 互动脂质细胞体中的脂肪体.分子动力学模拟模型糖的 Ester 是一种糖.

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Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
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