孕产妇血红蛋白度与在高资源产科环境中儿童中期的教育成就之间的关联:一项前性队列研究
Laurentya Olga1, Ulla Sovio1, Hilary Wong2
1Department of Obstetrics and Gynaecology, the Rosie Hospital and NIHR Cambridge Biomedical Research Centre, University of Cambridge, Cambridge, United Kingdom.
American journal of obstetrics & gynecology MFM
|March 25, 2024
概括
怀孕后期母亲的贫血与5岁儿童的教育成绩较低有关. 然而,这种联系并没有持续到更年长的童年,这表明干预措施可能不会影响长期的学业成功.
科学领域:
- 产科和妇科 产科和妇科
- 儿科神经发育 儿童神经发育
- 公共卫生 公共卫生
背景情况:
- 怀孕期间的母体血红蛋白水平与围产期的结果有关,但它们对儿童神经发育的影响尚不清楚.
- 现有研究尚未确定母亲的铁状况与后代的长期认知结果之间的关系.
研究的目的:
- 研究怀孕早期和晚期母亲血红蛋白水平与儿童中期教育成就之间的联系.
- 探索母亲贫血和血红蛋白度对后代学业成绩的影响.
主要方法:
- 潜在的出生队列研究 (怀孕结果预测研究,英国,N=3285) 与数据链接到儿童中期教育成果.
- 为分析关联,调整了对母亲,儿童和社会经济因素的回归模型.
- 在怀孕12周和28周评估母亲的血红蛋白,并在5-7岁时评估受教育程度.
主要成果:
- 在12周的孕产妇血红蛋白与不良妊娠结果或教育成就没有关联.
- 28周母亲血红蛋白较高与妊娠年龄较小的婴儿和早产的风险增加有关.
- 28周的母亲贫血与在5岁时未达到预期的教育标准 (aOR 1.42) 的风险更高,但在6-7岁时没有.
- 没有发现高母体血红蛋白或血红蛋白变化与教育程度的关联.
结论:
- 怀孕28周的母亲贫血与5岁的教育成绩下降有关,但在年龄较大时没有观察到这种影响.
- 在高资源环境中增加母亲血红蛋白的干预措施可能不会显著影响儿童的长期教育成果.
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