在肉瘤诊断之前的全科医院临床活动:一项澳大利亚队列研究
Meena Rafiq1, Jasper de Boer2, Jasmine Mar3
1Department of General Practice and Centre for Cancer Research, University of Melbourne, Melbourne, Australia, and Epidemiology of Cancer Healthcare and Outcomes (ECHO) Group, Department of Behavioural Science and Health, Institute of Epidemiology and Health Care (IECH), UCL, London, UK.
概括
患有肉瘤的患者在诊断前六个月开始增加了通用诊所访问和成像请求. 这种诊断窗口为早期瘤检测和改善患者治疗结果提供了机会.
科学领域:
- 在瘤学瘤学.
- 一般的做法一般的做法
- 医疗保健服务研究 医疗服务研究
背景情况:
- 迟到诊断的肉瘤与较差的患者预后有关.
- 识别在初级保健中加快肉瘤诊断的机会至关重要.
研究的目的:
- 为了调查一般实践 (GP) 在肉瘤诊断前期的临床活动.
- 为了确定早期发现肉瘤的潜在诊断窗口.
主要方法:
- 一项追溯的澳大利亚队列研究利用了链接的医院注册表 (ACCORD) 和初级保健数据 (Patron,MedicineInsight).
- 在诊断前一年的软组织肉瘤 (STS) 和骨肉瘤 (BS) 患者中比较医疗保健利用事件 (出席,处方,成像请求).
- 普森回归分析了诊断前24个月的每月发病率比率 (IRR),以确定医疗保健使用量的增加.
主要成果:
- 肉瘤患者从诊断前3个月开始增加了GP的出席率,从诊断前6个月开始增加了成像请求.
- 在诊断前6个月,33-36%的患者有GP成像请求,19-21%有多次请求.
- 从诊断前6个月起,GP成像请求增加了多达8倍 (IRR 8.43).
结论:
- 萨尔科马患者的临床活动在诊断前6个月开始,突出了关键的诊断窗口.
- 专注于识别有风险的患者和优化成像和转诊途径的干预措施可以促进早期诊断.
- 通过改进的初级保健途径,早期诊断肉瘤可以带来更好的患者结果.
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