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Updated: Jun 29, 2025

Neurodegeneration in an Animal Model of Chronic Amyloid-beta Oligomer Infusion Is Counteracted by Antibody Treatment Infused with Osmotic Pumps
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在阿尔茨海默氏病中,APP反感性寡核酸减少了粉样β聚合,并拯救了内分泌体功能障碍

Christy Hung1,2, Emre Fertan3, Frederick J Livesey2

  • 1Human Stem Cells and Neurodegeneration Laboratory, The Francis Crick Institute, London NW1 1AT, UK.

Brain : a journal of neurology
|March 25, 2024
PubMed
概括

在阿尔茨海默病模型中,针对APP基因的反意义寡核酸有效地减少了粉样β聚合物和细胞功能障碍. 这种方法为APP重复和与唐氏综合征相关的阿尔茨海默病提供了潜在的治疗方法.

关键词:
聚合方式 聚合方式 聚合方式粉样蛋白前体蛋白质是粉样蛋白的前体.自自是自的过程.内部体内体内体内体内体内体内体内体内这些是iPSCs.lysosome 溶解酶体是如何形成的

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