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Updated: Jun 29, 2025

In Vivo Modeling of the Morbid Human Genome using Danio rerio
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In Vivo Modeling of the Morbid Human Genome using Danio rerio

Published on: August 24, 2013

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发现人类病体中的遗传关联,使用内啡因型增强疾病网络

Jakob Woerner1,2, Vivek Sriram1,2, Yonghyun Nam1

  • 1Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States.

Bioinformatics (Oxford, England)
|March 25, 2024
PubMed
概括

我们开发了一种新型疾病网络模型 (ssDDN+),将遗传相关性与临床生物标志物集成在一起. 这种方法揭示了对心脏代谢障碍背后的共同遗传学的新见解,突出了HDL-C和甘油三作为关键的连接因素.

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A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports07:35

A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports

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