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与功能性食道疾病 (FED) 与胃食道逆流症 (GERD) 相关的危险因素
Moniyka Sachar1, Marina Mautner Wizentier2, Emma Risner2
1Department of Medicine, New York University Langone Health, 247 E 28th Street, New York, NY, 10016, USA. moniyka.sachar@nyulangone.org.
Surgical endoscopy
|March 26, 2024
概括
功能性食道障碍 (FED) 在体重BMI低,慢性疼痛,失眠,过敏性鼻炎或亚洲或西班牙裔种族的患者中更常见. 这些发现有助于临床医生识别患FED风险较高的个体.
科学领域:
- 胃肠病学 胃肠病学
- 食道生理学 食道生理学
- 功能性胃肠道疾病 功能性胃肠道疾病
背景情况:
- 胃食道逆流性疾病 (GERD) 症状很常见,但在监测时,30%的患者表现出功能性食道障碍 (FED).
- FED包括反流过敏症 (RH) 和功能性胃灼热 (FH),这些情况与生理酸暴露有关,但症状相关性各不相同.
- 对于FED存在有限的流行病学数据,促使对易感因素进行调查.
研究的目的:
- 调查与 FED 相关的人口,社会经济和并发症因素.
- 与病理性GERD相比,要区分FED的风险因素.
主要方法:
- 患有反流症状的成年患者接受了24小时pH阻抗测试.
- 根据阻抗数据和症状相关性,参与者被分为病态GERD,FH或RH.
- 追溯数据收集包括人口统计,保险状况和医疗并发症.
主要成果:
- 非西班牙裔亚洲族裔,体重不足BMI,慢性疼痛,失眠和过敏性鼻炎与增加FED风险有关.
- 超重的BMI和酒精消费与FED风险降低有关.
- 在女性性别和焦虑方面观察到较弱的关联,这与之前的研究一致.
结论:
- 这项研究确定了FED的新风险因素,包括特定的种族,体重不足BMI和某些并发症.
- 研究结果表明,临床医生可以更好地选患有反流症状的患者进行FEED.
- 了解这些关联可以帮助诊断和管理功能性食道障碍.
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