非酒精性脂肪性肝病和肥胖尼日利亚人的相关危险因素:一项横截面研究
C P Onyia1, P Asogwa1, W Adiri1
1Gastroenterology Unit, Department of Medicine, University of Nigeria Teaching Hospital, Ituku-Ozalla, Enugu, Nigeria.
Nigerian journal of clinical practice
|March 26, 2024
概括
非酒精性脂肪肝 (NAFLD) 影响了尼日利亚36.4%的肥胖个体. 关键的危险因素包括肥胖,高血压和糖尿病,这突显了严重的公共卫生问题.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 肥胖医学 肥胖医学
- 公共卫生 公共卫生
背景情况:
- 非酒精性脂肪性肝病 (NAFLD) 是全球慢性肝病的主要原因.
- NAFLD显著导致肝细胞癌的发病率增加.
- 在尼日利亚,NAFLD的患病率及其对肝病负担的影响在很大程度上仍未被描述.
研究的目的:
- 确定肥胖个体中NAFLD的流行率.
- 为了确定与该人口中NAFLD相关的风险因素.
主要方法:
- 一项涉及280名肥胖者和280名非肥胖者的横截面研究.
- 通过问卷,人体测量和生物化学测试收集的数据.
- 腹部超声波用于NAFLD查.
主要成果:
- 与对照组 (0.4%) 相比,肥胖者 (36.4%) 的NAFLD患病率明显高.
- 肥胖程度,过氨基酶水平升高,高脂血症,高血压和糖尿病与NAFLD有关.
- 代谢综合征在患有NAFLD (65.9%) 的肥胖个体中明显更为普遍.
结论:
- 在尼日利亚,NAFLD在肥胖个体中具有显著的流行率.
- 肥胖,高脂血症,高血压和糖尿病是NAFLD的主要相关因素.
- 这些发现强调了针对肥胖人口的有针对性的干预措施的必要性.
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