癌症早期免疫疗法试验参与者的决策和自主性:一种定性研究
Jonathan Avery1,2, Jennifer A H Bell3,4,5,6,7, Khotira Baryolay2
1School of Nursing, University of British Columbia, Vancouver, BC, Canada.
BMC cancer
|March 26, 2024
概括
患者 患者 患者 患者
科学领域:
- 在瘤学瘤学.
- 生物伦理学生物伦理学
- 定性研究是指质量研究.
背景情况:
- 了解早期癌症临床试验 (CTs) 的风险和益处对于知情同意至关重要.
- 关系自主性是分析癌症CTs患者决策的关键伦理框架.
- 早期癌症免疫疗法CT对参与者提出了独特的考虑.
研究的目的:
- 探索影响患者决定早期癌症免疫疗法CT参与的因素.
- 通过关系自主性的伦理镜头来分析这些决定.
主要方法:
- 使用解释性描述性设计进行定性研究.
- 对21名癌症晚期的成年患者进行了采访,这些患者参加了早期CTs.
- 使用关系自主理论和常数比较分析分析的数据.
主要成果:
- 在早期癌症免疫疗法CT中,对选择的看法因绝望与机会而异.
- 心理社会和结构因素影响了决策,包括希望,信任,戒断能力和时间.
- 在考虑这些试验的患者中存在连续的感知选择.
结论:
- 所有参与者都在CT环境中表现出一定程度的关系自主性.
- 调查结果为实践和政策提供了信息,以更好地支持早期癌症免疫疗法CT的知情决策.
- 突出了癌症护理,患者价值观和CT结构的交集.
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