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评估来自印度各地的三级医院的处方,以发现与治疗指南的偏差及其潜在后果
Yashashri Shetty1, Sandhya Kamat1, Raakhi Tripathi1
1Department of Pharmacology & Therapeutics, Seth GSMC & KEM Hospital, Mumbai, Maharashtra, India.
The Indian journal of medical research
|March 26, 2024
概括
近10%的处方显示出不可接受的偏差,导致成本增加和药物不良反应. 建议采取在线培训和行政命令等干预措施,以改善合理的处方实践.
科学领域:
- 药理学 药理学是指药理学的学科.
- 临床药房 临床药房
- 公共卫生 公共卫生
背景情况:
- 不合理的处方做法显著影响患者安全和医疗保健成本.
- 了解与治疗指南的偏差对于改善处方至关重要.
- 关于处方偏差的现实数据可以为更好的临床实践提供信息.
研究的目的:
- 评估处方中偏离标准治疗指南的普遍性.
- 为了确定这些处方偏差的潜在后果.
- 为了捕捉临床医生推的纠正行动.
主要方法:
- 在印度的三级护理医院进行了一项横截面观察性研究.
- 处方被评估是否符合标准治疗指南.
- 导致药物相互作用,缺乏反应,增加成本,药物不良反应 (ADR) 或抗菌素耐药性的偏差被归类为不可接受.
主要成果:
- 总体而言,45%的处方有偏差,其中9.8%被归类为不可接受.
- 与不可接受的偏差相关的常见处方药包括潘托普拉和拉贝普拉+多姆佩里.
- 发现的潜在后果包括成本增加 (301),副作用 (254),药物相互作用 (81),缺乏治疗反应 (77) 和抗菌素耐药性 (72).
结论:
- 无法接受的处方偏差对患者安全构成重大风险,并增加医疗保健支出.
- 临床医生推在线培训计划和行政指令,以尽量减少偏差.
- 提高合理的处方对于优化患者的治疗结果和资源利用至关重要.
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