人类母乳微生物组:与母亲的饮食和婴儿生长的关联
Tamara T Ajeeb1,2, Emmanuel Gonzalez3,4,5, Noel W Solomons6
1School of Human Nutrition, McGill University, Montreal, QC, Canada.
Frontiers in nutrition
|March 26, 2024
概括
母亲的饮食通过改变人乳微生物群 (HMM) 来影响婴儿的生长. 这项研究发现,在危地马拉的母婴双中,母婴营养素,HMM成分和婴儿生长标志物之间存在明显的相关性.
科学领域:
- 微生物学 微生物学
- 人类营养人类营养
- 儿科 儿科 儿科
背景情况:
- 人类乳 (HM) 对婴儿肠道微生物殖民至关重要,影响健康和发育.
- 孕产妇的饮食与人乳微生物群 (HMM) 有关,但其对婴儿生长的综合影响还未得到充分研究.
研究的目的:
- 调查早期哺乳期玛雅母婴双中母亲饮食,HMM组成和婴儿生长之间的关联.
主要方法:
- 在危地马拉,对64个母婴双进行了横截面研究.
- 收集的孕产妇饮食数据 (24小时回忆) 和HMM样本 (16S rRNA基因测序).
- 使用z-score (头周长,长度,体重) 评估婴儿生长,并分析差异丰富的HMM taxa.
主要成果:
- 在母亲的饮食模式和婴儿生长集群之间发现了积极的相关性.
- 母亲的营养摄入量与特定的HMM物种有不同的关联.
- 观察到HMM种群,母体营养素和婴儿生长z-score之间的明显相关性,正常生长和生长迟缓的婴儿之间存在差异.
结论:
- 母亲的饮食通过调节HMM显著影响婴儿早期生长.
- 这些发现突出了母亲的营养,牛奶微生物组和婴儿发育之间的复杂关系.
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