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与腰部疼痛相对应的大脑变化:最近的见解和进展

Xuyang Li¹, Fancheng Meng¹, Wenye Huang^1,2

¹Department of Neurobiology and Collaborative Innovation Center for Brain Science, School of Basic Medicine, The Fourth Military Medical University, Xi'an, China.

Neural plasticity

|March 26, 2024

概括

腰部疼痛 (LBP) 涉及大脑结构和功能的变化. 神经成像显示白质,灰质和神经回路的变化,影响LBP发展和情感福祉.

科学领域:

神经科学是一个神经科学.
疼痛医学医学疼痛医学
放射学放射学是一门学科.

背景情况:

腰部疼痛是全球残疾的主要原因之一.
从历史上看,LBP的神经变化主要集中在外围神经和脊髓上.
腰痛对大脑结构和功能的影响需要进一步研究.

研究的目的:

审查当前关于与慢性腰部疼痛相关的大脑变化的研究结果.
探索大脑变化和LBP病因之间的关系.
为新的诊断和治疗方法提供见解.

主要方法:

审查使用非侵入性神经成像技术的现有临床研究.
对大脑结构和神经回路中发现的异常进行分析.
大脑结构和功能连接与LBP发生和进展的相关性.

主要成果:

慢性LBP与白质,灰质和神经回路的改变有关.
大脑结构和功能连接的异常与LBP相关.
与背部疼痛相关的负面情绪表明情绪大脑区域的变化.

结论:

大脑的改变是理解腰部疼痛不可或缺的组成部分.
研究结果支持LBP,大脑变化和情绪障碍之间的联系.
这一综述为LBP诊断和治疗提供了综合医学方法的基础.

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