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Updated: Jun 20, 2026

Production of Transgenic Xenopus laevis by Restriction Enzyme Mediated Integration and Nuclear Transplantation
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Production of Transgenic Xenopus laevis by Restriction Enzyme Mediated Integration and Nuclear Transplantation

Published on: August 21, 2010

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在Xenopus laevis的发育过程中,T3和T4的重叠作用

Alicia Tribondeau1, David Du Pasquier2, Médine Benchouaia3

  • 1Unité Mixte de Recherche 7221, Département Adaptation du Vivant, Centre National de la Recherche Scientifique, Muséum National d'Histoire Naturelle, Alliance Sorbonne Universités, Paris, France.

Frontiers in endocrinology
|March 26, 2024
PubMed
概括

甲状腺激素调节关键的生物过程. 内分泌干扰剂可以干扰这种信号传递,影响健康. 这项研究使用Xenopus幼来分析由甲状腺激素诱导的基因表达变化,确定对细胞周期和免疫系统的影响.

关键词:
在Xenopus Eleutheroembryonic甲状腺检测中使用.它们是 Xenopus laevis 的类型.细胞的增殖细胞的增殖.甲状腺激素 甲状腺激素文字转录 字体转录 字体转录

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X-Inactivation01:58

X-Inactivation

The human X chromosome contains over ten times the number of genes as in the Y chromosome. Since males have only one X chromosome, and females have two, one might expect females to produce twice as many of the proteins, with undesirable results.
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Inheritance of Chromatin Structures

Epigenetics is the study of inherited changes in a cell's phenotype without changing the DNA sequences. It provides a form of memory for the differential gene expression pattern to maintain cell lineage, position-effect variegation, dosage compensation, and maintenance of chromatin structures such as telomeres and centromeres. For example, the structure and location of the centromere on chromosomes are epigenetically inherited. Its functionality is not dictated or ensured by the underlying DNA...
Dosage Compensation02:50

Dosage Compensation

In animals, gender is determined by the number and type of sex chromosome. For example, human females have two X chromosomes, and males have one X and one Y chromosome, whereas C.elegans with one X chromosome is a male, and the one with two X chromosomes is a hermaphrodite.
In addition to sexual development, the X chromosome has genes involved in autosomal functions such as brain development and the immune system. Therefore, males and females with  distinct numbers of X chromosomes will have...
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Synthesis and Regulation of Thyroid Hormones

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Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The iodine is then...