儿科瘤患者的维生素D缺乏:沙特阿拉伯的一个单一中心的经验
Dania A Monagel1,2,3, Amal O Albaity1, Fatimah M Asiri1
1College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Cureus
|March 26, 2024
概括
超过三分之二的儿童癌症患者在诊断时缺乏维生素D或缺乏维生素D. 较年长的儿童和女性更容易受到影响,强调需要对补充剂和阳光照射的教育.
科学领域:
- 儿科瘤学 儿科瘤学
- 内分泌学 在内分泌学.
- 营养科学 营养科学
背景情况:
- 关于儿童癌症患者维生素D缺乏的局部数据有限.
- 维生素D缺乏是全球儿科瘤学中日益关注的问题.
- 了解患病率对于改善临床护理和研究至关重要.
研究的目的:
- 确定在吉达国王阿卜杜勒-阿齐兹医疗城 (KAMC) 的儿科瘤患者中维生素D缺乏症的患病率.
- 为了确定影响该群体维生素D水平的因素.
- 解决知识差距,以改善患者管理.
主要方法:
- 从2016-2021年进行的回顾性观察研究.
- 包括155名儿科瘤患者 (在诊断时≤14岁).
- 对人口统计,癌症细节,治疗和血清维生素D (25(OH) D),,酸盐和性酸酶水平的分析.
主要成果:
- 63%的患者在诊断时有维生素D缺乏/不足,治疗后降至43%.
- 年龄较大的儿童和女性在诊断时的维生素D水平较低,治疗后差异减少.
- 患有血性恶性瘤的患者的维生素D水平比患有固体瘤的患者低.
结论:
- 儿童癌症患者中很大一部分患有维生素D缺乏/不足.
- 血液和固体瘤患者的基线维生素D水平不同.
- 对于儿科瘤患者来说,对维生素D补充和阳光照射的教育至关重要.
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