环状皮质塑造了社会发声的早期产后发展.
Gurueswar Nagarajan1, Denis Matrov1, Anna C Pearson1
1Section on Behavioral Neuroscience, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, USA.
bioRxiv : the preprint server for biology
|March 26, 2024
概括
马尔莫塞特前带带皮层 (ACC) 的早期损伤损害了社会发声的发展. 这个大脑区域对于语音沟通和社会情绪调节至关重要.
科学领域:
- 神经科学是一个神经科学.
- 发展生物学 发展生物学
- 灵长类动物学 灵长类动物学
背景情况:
- 社会声音行为对于发展至关重要.
- 前带带皮层 (ACC) 与社会情绪调节有关.
- 了解早期脑损伤对发声的影响很重要.
研究的目的:
- 为了调查早期生活中ACC损伤是否会影响小熊猫的声音表达发育.
- 检查ACC病变对社会发声的长期影响.
主要方法:
- 新生儿的海得到了ACC病变.
- 在6周的时间里,在受伤者和对照组之间比较了发声.
- 在成年人中分析了下游的大脑区域 (桃体,周水管灰色).
主要成果:
- 早期的ACC病变并没有影响语音呼叫的产生,但改变了呼叫质量.
- 受伤的海会产生更少,更大声和更单调的社交联系电话.
- 患有ACC损伤的成年人在社交发声的大脑区域显示出改变的GABA免疫活性.
结论:
- ACC对于社会声乐行为的正常发展至关重要.
- 早期的ACC损伤会破坏声网络的相互作用,并导致持久的变化.
- 在社会情绪调节中ACC的作用与语音沟通发展交织在一起.
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