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Updated: May 12, 2026

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阿斯帕拉基尼尔内酶介导的循环化用于菌体显示

Xiao-Cui Wan1, Yan-Ni Zhang1, Hua Zhang1

  • 1School of Life Science, Institutes of Physical Science and Information Technology, Institute of Health Sciences, Anhui University, Hefei 230601, P.R. China.

Organic letters
|March 26, 2024
PubMed
概括

研究人员使用阿斯帕拉基尼尔内多酶开发了一种酶化方法,用于类循环. 这一策略与菌体显示相结合,产生了向TEAD4的强大的宏环配体,对药物发现具有很高的亲和力.

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