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皮埃佐1通道抑制ILC2s,并调节气道过敏反应的发展

Benjamin P Hurrell1, Stephen Shen1, Xin Li1

  • 1Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

The Journal of experimental medicine
|March 26, 2024
PubMed
概括

肺部的Piezo1通道限制了由2组先天性淋巴细胞 (ILC2) 驱动的2型炎症. 用Yoda1激活Piezo1,可以通过减少ILC2功能和呼吸道过敏反应来治疗过敏喘.

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