电子尼古丁输送系统替代对体重状况的影响:系统审查和元分析议定书
Giusy Rita Maria La Rosa1,2, Maria Ahmed Qureshi1,2, Lucia Frittitta1,2,3
1Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
JMIR research protocols
|March 26, 2024
概括
电子尼古丁输送系统 (ENDS) 可能有助于戒烟后的体重管理,但证据相互矛盾. 这次系统性审查和元分析将澄清ENDS.
科学领域:
- 公共卫生和预防医学
- 临床药理学和毒理学
- 行为医学是一种行为医学.
背景情况:
- 由于尼古丁的代谢作用,戒烟后体重增加是一个常见的担忧.
- 电子尼古丁输送系统 (ENDS) 是建议的戒烟和控制体重的辅助工具.
- 现有审查中的相互矛盾的结论需要对ENDS对体重状况的影响进行严格评估.
研究的目的:
- 系统地审查和元分析ENDS对前吸烟者或减少吸烟者的体重状况的影响.
- 为临床医生提供基于证据的见解,了解ENDS在减肥后的使用.
- 评估目前关于ENDS和重量的研究的质量和潜在偏见.
主要方法:
- 按照PRISMA-P指南进行系统审查和元分析.
- 包括随机对照试验,非随机对照试验,临床试验和队列研究 (2010-2024年).
- 在PubMed,Scopus,Cochrane图书馆进行搜索;使用Joanna Briggs研究所工具进行质量评估;进行元分析和子组分析.
主要成果:
- 在PROSPERO注册的协议 (CRD42023494974);预计在2024年4月完成全面审查.
- 旨在综合当前关于ENDS对吸烟后体重管理的影响的人类研究.
- 综合质量和偏见评估,以确定最可靠的证据.
结论:
- 该审查将综合有关ENDS在戒烟期间对体重状况的影响的强有力的证据.
- 调查结果将为医疗保健专业人员和患者提供有关向ENDS过渡的影响的信息.
- 这项研究对于基于证据的关于ENDS作为戒烟工具的指导至关重要.
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