自动异时态晚期激活映射用于基质特征在患者修复的Fallot四重律的患者
Eduardo Arana-Rueda1,2,3, Juan Acosta1,3, Manuel Frutos-López1,3
1Arrhythmia Unit, Department of Cardiology, Hospital Universitario Virgen del Rocío, Avda. Manuel Siurot, s/n, Sevilla 41013, Spain.
概括
对同时晚期激活图的自动化分析准确地识别了Fallot患者修复的四重律中的缓慢导电解剖峡. 这使得可以安全有效地对心室动脉动脉基质进行表征.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 医疗器械 医疗器械
背景情况:
- 缓慢导电 (SC) 解剖脉冲 (AIs) 是单形心室性心力衰竭 (VT) 的主要基质,患者有修复的Fallot四心法 (rTF).
- 准确识别这些SC-AI对于有效的VT管理在这个人群中至关重要.
研究的目的:
- 评估使用同时晚期激活地图 (ILAM) 来识别rTF患者SC-AI的自动传播分析的实用性.
- 评估自动发现与VT基质特征之间的相关性.
主要方法:
- 连续的rTF患者接受了静脉瘤基质表征被包括在内.
- 在鼻腔节律过程中,使用多电极高频电网导管生成自动ILAM.
- 识别的减速区 (DZs) 与SC-AI (通过传导速度<0.5 m/s定义) 和VT峡谷进行了比较.
主要成果:
- 自动化的ILAM在识别SC-AIs时以高精度 (90%的灵敏度,100%的特异性) 检测到减速区 (DZs).
- 在同位素/厘米数量和导电速度 (rho -0.87;P < 0.001) 之间观察到显著的负相关性.
- 在88%可诱导的静脉位中,DZ与关键静脉位同定位,它们的存在与静脉位的诱导性有关 (P = 0.006).
结论:
- 自动ILAM衍生减速区准确地识别rTF患者的SC-AI.
- 这种自动化方法允许安全,快速和有效的VT基质表征.
- 这些发现支持将自动传播分析纳入rTF患者的常规电生理学程序.
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