心脏病患者的隐蔽脑血管变化:系统性审查和元分析
Zien Zhou1, Shoujiang You1, Yuki Sakamoto1
1From the The George Institute for Global Health (Z.Z., S.Y., Y.S., Y.X., J.Y., Y.W., K.H., C.D., M.W., C.A., C.C.), Faculty of Medicine, University of New South Wales, Sydney, Australia; Department of Neurology and Clinical Research Center of Neurological Disease (S.Y.), The Second Affiliated Hospital of Soochow University, Suzhou, PR China; Department of Neurological Science (Y.S.), Graduate School of Medicine, Nippon Medical School, Tokyo, Japan; Centre for Health Systems and Safety Research (Y.X.), Australian Institute of Health Innovation, Macquarie University, Sydney, Australia; Department of Cardiology (S.D., W.X., J.P.), Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University; Department of Cardiology (W.L., X.D.), Beijing Anzhen Hospital, Capital Medical University; Department of Cardiology (J.Y.), Peking University Third Hospital, Beijing; Department of Neurology (Y.W.), West China Hospital, Sichuan University, Chengdu, PR China; Department of Clinical Medicine (C.D.), Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, Australia; Department of Epidemiology and Biostatistics (M.J.R.), College of Human Medicine, Michigan State University, East Lansing; The George Institute for Global Health and University of Sydney (R.I.L.); South Western Clinical School (M.W.P.), University of New South Wales, Sydney, Australia; The George Institute for Global Health (M.W.), School of Public Health, Imperial College London, United Kingdom; Department of Neurology (C.A., C.C.), Royal Prince Alfred Hospital, Sydney Health Partners, Australia; Edinburgh Imaging and Centre for Clinical Brain Sciences (J.M.W.); and UK Dementia Research Institute (J.M.W.), University of Edinburgh, United Kingdom.
患有心脏病的成年人患有沉默性脑梗塞 (SBI) 和大脑小血管疾病 (CSVD) 的患病率很高. 这些情况在最近中风或没有中风的人中同样普遍存在,这表明需要进一步研究.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 流行病学 流行病学
背景情况:
- 在患有各种心脏病的成年人中调查静音脑梗塞 (SBI) 和大脑小血管疾病 (CSVD) 的患病率.
- 在最近中风和没有中风的个人之间比较SBI和CSVD的患病率.
- 探索心脏病与SBI/CSVD存在之间的关联.
结论:
- 患有心脏病的个人表现出大量的SBI和CSVD负担.
- 最近中风的存在似乎不会改变这个人群中的SBI患病率.
- 需要进一步的研究来阐明因果关系,并为临床管理策略提供信息.
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