相关实验视频

Updated: Jun 29, 2025

Automated Measurement of Cryptococcal Species Polysaccharide Capsule and Cell Body

Automated Measurement of Cryptococcal Species Polysaccharide Capsule and Cell Body

Published on: January 11, 2018

酵母细胞壁囊用于输送麦生物标志物阿维南特拉米德-C

Linyang He¹, Yubo Zhu¹, Xinghui Shen¹

¹Key Laboratory of Geriatric Nutrition and Health (Beijing Technology and Business University), Ministry of Education, China-Canada Joint Lab of Food Nutrition and Health, Beijing Technology and Business University (BTBU), Beijing 100048, China.

|March 26, 2024

概括

酵母细胞壁囊有效地稳定了麦生物标记物Avenanthramide-C (AVN-C),提高了其生物可用性. 这些新型的输送系统为功能性食品和营养保健品中的AVN-C提供了潜力.

科学领域:

食品科学与技术食品科学与技术
生物材料工程生物材料工程
营养学药物开发

背景情况:

麦的关键生物标志物AVN-C具有各种生理益处,但稳定性和生物利用性不佳.
目前的局限性阻碍了AVN-C在食补充剂和功能性食品中的实际应用.

研究的目的:

研究酵母细胞 (YC) 和酵母细胞壁 (YCW) 囊作为稳定AVN-C.的输送系统的疗效.
评估这些基于酵母的输送系统中的AVN-C的封装效率,装载能力和释放特性.

主要方法:

使用显微镜对酵母囊的形态和结构进行表征.
在YC和YCW系统中对AVN-C封装和加载的量化.
在模拟胃肠道条件下评估AVN-C释放动力学.
酵母囊与AVN-C.之间的相互作用分析.

主要成果:

酵母囊表现出圆形形态,结构完好,没有可见的毛孔.
与YC囊相比,YCW囊表现出更高的封装和装载能力,这是由于内部体积更大.
相互作用涉及疏水力和键,加载AVN-C增加囊疏水性.
在模拟的胃肠环境中,AVN-C的释放速度缓慢且持续,这表明稳定性得到了增强.

结论:

酵母细胞壁 (YCW) 囊显示出作为Avenanthramide-C (AVN-C) 有效的受控输送系统的巨大潜力.
这种稳定策略可能有助于将AVN-C纳入营养药和功能性食品,从而改善其治疗和健康益处.

关键词:

一个阿文胺-C.生物标志物生物标志物交付系统的交付系统.酵母囊酵母囊是一种酵母细胞壁中的酵母细胞壁.

更多相关视频

Small-Scale Plasma Membrane Preparation for the Analysis of Candida albicans Cdr1-mGFPHis

Small-Scale Plasma Membrane Preparation for the Analysis of Candida albicans Cdr1-mGFPHis

Published on: June 13, 2021

Preparation of Fungal and Plant Materials for Structural Elucidation Using Dynamic Nuclear Polarization Solid-State NMR

Preparation of Fungal and Plant Materials for Structural Elucidation Using Dynamic Nuclear Polarization Solid-State NMR

Published on: February 12, 2019

相关概念视频

Yeast Signaling

Yeast Signaling

Yeasts are single-celled organisms, but unlike bacteria, they are eukaryotes (cells with a nucleus). Cell signaling in yeast is similar to signaling in other eukaryotic cells. A ligand, such as a protein or a small molecule released from a yeast cell, attaches to a receptor on the cell surface. The binding stimulates second-messenger kinases to activate or inactivate transcription factors that further regulate gene expression. Many of the yeast intracellular signaling cascades have similar...

Cellulose and Pectic Polysaccharides

Cellulose and Pectic Polysaccharides

Every plant cell has a cell wall that protects the cell, provides structural support, and gives the cell shape. Cellulose, the main structural component of the plant cell wall, makes up over 30% of plant matter. It is the most abundant organic compound on earth. Cellulose is an unbranched polysaccharide composed of linear chains of glucose molecules linked by β (1→4) glycosidic bonds.
As a cell matures, its cell wall specializes according to its type. For example, the...

Role of Microtubules in Cell Wall Deposition

Role of Microtubules in Cell Wall Deposition

Microtubules are small hollow tubes in eukaryotic cells. The cell wall microtubules are polymerized dimers of two globular proteins, α-tubulin and β-tubulin, two globular proteins. With a diameter of about 25 nm, microtubules are the widest components of the cytoskeleton. They help the cell resist compression and provide a track along which vesicles move through the cell or pull replicated chromosomes to opposite ends of a dividing cell. Microtubules go through quick cycles of...