相关实验视频
Updated: Jun 29, 2025

07:13
Measuring Active and Passive Tameness Separately in Mice
Published on: August 10, 2018
7.2K
在设计猫品种中的祖先动态和特征选择
Christopher B Kaelin1, Kelly A McGowan1, Anthony D Hutcherson2
1HudsonAlpha Institute for Biotechnology, Huntsville, AL 35806, USA; Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.
Current biology : CB
|March 26, 2024
概括
孟加拉猫具有来自猫杂交的独特特征. 基因组分析显示,猫DNA广泛分布,但没有强烈选择,除了特定的颜色特征和猫DNA外.
科学领域:
- 遗传学 是一个遗传学.
- 动物科学动物科学
- 动物学 动物学
背景情况:
- 孟加拉猫的品种起源于亚洲猫 (Prionailurus bengalensis) 和家猫 (Felis catus) 之间的杂交.
- 品种特征,包括独特的皮肤和颜色模式,归因于猫基因组的内进区域.
研究的目的:
- 调查孟加拉猫基因组中的祖先分布和选择特征.
- 为了确定特定的孟加拉猫特征的遗传基础,如外套颜色和图案.
主要方法:
- 在947只孟加拉猫的队列上利用了减少的表示和全基因组测序.
- 分析了祖先比例,并确定了与猫DNA内进相关的选择性扫描.
主要成果:
- 孟加拉猫中猫DNA的平均比例为3.48%,广泛分布在93%的基因组中.
- 猫DNA的内侵并没有表现出强烈的全基因组选择特征.
- 特定的特征,如木炭颜色和叶黑素强度,与特定的猫基因有关,在家猫背景下表达减少.
- 鉴定了一种选择性扫除,与Fgfr2基因的表达减少有关,Fgfr2基因负责"闪闪发光"外套特征.
结论:
- 杂交导致猫在孟加拉猫中广泛但未经严格选择的猫遗传贡献.
- 特定的颜色特征和"闪闪发光"的外套表型受到选定的猫基因和遗传不相容性的影响.
- 这项研究阐明了孟加拉猫的关键特征的遗传基础,提供了对杂交和品种发展的见解.
相关概念视频
Types of Selection
40.4K
Natural selection influences the frequencies of particular alleles and phenotypes within populations in several different ways. Primarily, natural selection can be directional, stabilizing, or disruptive. Directional selection favors one extreme trait and shifts the population towards that phenotype while selecting against individuals displaying alternate traits. Stabilizing selection favors an intermediate trait with a narrow range of variation. Deviation from the optimal phenotype towards an...
40.4K
Mate Choice
8.0K
Mate choice—the decision about whom to mate with—is a type of natural selection, since animals must reproduce to pass down their genes. Mate choice is also called intersexual selection because the behavior occurs between the sexes.
8.0K
Incomplete Dominance
22.5K
Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.
22.5K
Behavioral Genetics and Its Designs
363
Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
363
Background and Environment Affect Phenotype
6.5K
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
6.5K
Natural Selection and Mating Preferences
102
The principle of natural selection posits that organisms better adapted to their environment are more likely to survive and reproduce. This principle is closely intertwined with mating preferences, a key aspect of sexual selection, which evolutionary psychologists believe is driven by instincts to propagate one's genes. Such instincts significantly influence mating behaviors and preferences between genders.
Females, due to their biological roles in conception, pregnancy, and nursing,...
Females, due to their biological roles in conception, pregnancy, and nursing,...
102

