骨肌松剂作为心胸外科手术后的辅助疼痛控制:一个系统审查协议
Shadman Kabir1, Quinn Whaley2, Melissa Fernandez2
1College of Osteopathic Medicine, Nova Southeastern University Health Professions Division, Fort Lauderdale, Florida, USA.
BMJ open
|March 26, 2024
概括
非去极化骨肌松剂可能会增强心胸外科手术后的多模式疼痛控制. 本系统性审查评估了它们在减少成人患者疼痛和阿片类药物使用方面的有效性.
科学领域:
- 麻醉学和疼痛管理
- 术后恢复 术后恢复
- 药理学 药理学是指药理学的学科.
背景情况:
- 在心胸外科手术后,多模式疼痛管理至关重要,国际指南强调其重要性.
- 非去极化骨肌松剂正在作为治疗术后疼痛的潜在辅助疗法进行研究.
- 在这种患者群体中优化疼痛控制可以显著影响恢复并减少并发症.
研究的目的:
- 系统地审查人类成年人对非去极化骨肌肉松剂在心胸手术后疼痛控制的疗效的研究.
- 评估这些药物对疼痛管理质量和减少阿片类药物消费的影响.
- 将研究结果与国际实践指南中建议的当前疼痛管理策略进行比较.
主要方法:
- 一个系统的综述发表在PubMed,Cochrane中央,科学网络和EMBASE的研究.
- 纳入标准:成人人体研究,心脏或胸部手术后1周内控制疼痛,使用非去极化骨肌松剂.
- 研究选择遵循系统审查和元分析 (PRISMA) 准则的首选报告项目;数据分析包括元分析.
主要成果:
- (等待研究完成) 从选定的研究数据的分析将量化非分极化骨肌肉松剂对疼痛评分的影响.
- (等待研究完成) 对阿片类药物需求和与使用相关的不良事件的影响评估.
- (等待研究完成) 结果与已建立的多式联络疼痛控制协议进行比较.
结论:
- (预计) 非去极化骨肌肉松剂可能为心胸外科手术中的多模式疼痛管理策略提供有价值的补充.
- (预计) 证据将为临床实践提供有关使用这些药物的信息,以改善患者的治疗结果和减少阿片类药物依赖.
- (预计) 进一步的研究可能会完善这些辅助疗法的最佳剂量和时间.
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