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在Blaps polychresta上的纳米钻石的全面毒性评估:含义和新发现

Marwa Saad¹, Nabila Selim¹, Lamia M El-Samad¹

¹Faculty of Science, Department of Zoology, Alexandria University, Alexandria, Egypt.

|March 26, 2024

概括

纳米钻石 (NDs) 具有毒理学风险,在黑色虫Blaps polychresta.中引起显著的器官损伤,DNA损伤和细胞死亡. 这项研究突出了NDs.

科学领域:

环境毒理学环境毒理学
纳米材料的安全性
昆虫毒理学昆虫毒理学

背景情况:

纳米材料,包括纳米钻石 (NDs),越来越多地使用,引发了人们对其生态影响的担忧.
由于它们的潜在生态系统透,了解NDs的毒理风险至关重要.

研究的目的:

为了研究纳米钻石 (NDs) 对黑色虫的有毒作用,Blaps polychresta.
评估NDs对生存,器官结构,酶活动,细胞活力和DNA完整性的影响.

主要方法:

在注射NDs后对Blaps多重的生存分析.
甲状腺学,超结构 (TEM,SEM) 和甲虫器官 (丸,卵巢,中肠) 的光显微镜.
评估酶活动,抗氧化系统,细胞活力 (流细胞计) 和DNA损伤 (彗星测定).

主要成果:

暴露于NDS导致了酶活性和抗氧化剂系统调节失调的显著干扰.
流式细胞计量显示,在NDs治疗的甲虫中,细胞活力下降,细胞亡/亡增加.
组织学和彗星测定分析显示了大量的DNA损伤和器官形.

结论:

纳米钻石在Blaps多重中产生显著的毒理效应,影响生存,器官完整性和遗传物质.
布拉普斯多色作为一个有价值的生物指标,用于评估纳米钻石的生态风险.
这项研究为NDs对陆地无脊椎动物的不利影响提供了关键的见解.

关键词:

布拉普斯是多色彩的生态毒性生态毒性分子分析分子分析纳米钻石是一种纳米钻石.氧化应激是一种氧化应激.病理生理学病理生理学

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