丰富的双倍细菌和乳酸菌作为潜在的食补充剂
Iva Mrvikova1,2, Ivana Hyrslova1,2, Antonin Kana3
1Department of Microbiology and Technology, Dairy Research Institute Ltd, Prague, Czech Republic.
World journal of microbiology & biotechnology
|March 27, 2024
概括
一些益生菌细菌,包括乳酸菌和双菌,可以将化转化为有益的纳米粒子 (SeNPs). 这些化菌株表现出抗氧化活性和疏水性变化,为提供了潜在的新来源.
科学领域:
- 微生物学 微生物学
- 生物技术是生物技术.
- 食品科学 食品科学 食品科学
背景情况:
- 乳酸菌和双菌等益生菌因其健康益处而闻名.
- 是一种必不可少的微量元素,具有抗氧化特性.
- 微生物通过无机生物转化为有机形式或纳米粒子是一个越来越感兴趣的领域.
研究的目的:
- 调查乳酸菌和双菌菌株积累和生物转化化到各种物种,包括纳米粒子 (SeNPs) 的能力.
- 评估人类腺癌细胞系 (Caco-2和HT29) 上的化菌株的耐受性和细胞毒性.
- 评估丰富对细菌菌株抗氧化活性和细胞表面疏水性的影响.
主要方法:
- 精选的乳酸菌和双菌菌株在补充不同度酸的介质中培养.
- 分析了的积累和生物转化成不同的物种,包括SeNPs.
- 使用暴露于化细菌菌株的Caco-2和HT29细胞进行了细胞毒性测试.
- 测量了化菌株的抗氧化活性和细胞表面水性.
主要成果:
- 所有测试的细菌菌株都表现出能够积累和生物转化化为物种的能力,包括大量的SeNPs,化和甲.
- 丰富改变了细菌菌株的抗氧化潜力和疏水性,L. paracasei显著增加,L. helveticus显著减少.
- 与较高度 (30-100 mg/L) 相比,化的5和10 mg/L度对Caco-2和HT29细胞生长更安全,这降低了细胞活力.
结论:
- 乳酸菌和双菌菌株具有将无机生物转化为各种形式的能力,包括SeNPs.
- 化益生菌细菌表现出改变的生物特性,如抗氧化活性和细胞表面特征.
- 这些发现表明,化益生菌可以作为补充的有希望和潜在的更安全的来源.
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