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Updated: Jun 29, 2025

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HyCas9-12aGEP:一个高效的基因组编辑平台用于Corynebacterium glutamicum

Feng Zhang1, Jin-Yu Wang1, Chang-Lon Li1

  • 1The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, China.

Frontiers in bioengineering and biotechnology
|March 27, 2024
PubMed
概括

一个新的混合CRISPR-Cas9-Cas12a基因组编辑平台 (HyCas9-12aGEP) 增强了Corynebacterium glutamicum的基因组重编程. 该工具提高了编辑分辨率和效率,优于现有的CRISPR技术.

关键词:
在Corynebacterium glutamicum的研究中,我们发现有活性的gRNARNA.编辑效率 编辑效率 编辑效率编辑解决方案的编辑这就是hfgRNA.

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