辅助生殖技术 (ART) 并不是在奥地利维也纳单期分娩中部呈现的独立风险因素
L Bartsch1, M Hämmerle1, S Putschögl1
1Department of Evolutionary Anthropology, University of Vienna, Vienna, Austria.
Journal of biosocial science
|March 27, 2024
概括
像IVF和ICSI这样的辅助生殖技术 (ART) 并没有显著增加单独分娩中部呈现的风险. 诸如年龄和性别等母亲因素与部呈现有更强烈的关联.
科学领域:
- 产科和妇科 产科和妇科
- 生殖医学 生殖医学
- 围产期流行病学 围产期流行病学
背景情况:
- 辅助生殖技术 (ART),包括体外受精 (IVF) 和细胞内精子注射 (ICSI),是研究的关键领域.
- 关于ART和产科并发症 (如部呈现) 之间的潜在关联,目前仍在进行辩论.
研究的目的:
- 为了研究ART受孕和部表现在单期分娩之间的关联.
- 为了确定通过ART与自发受孕怀孕的怀孕中部呈现的风险因素.
主要方法:
- 一个基于医疗记录的单中心研究,对11,920个单期分娩 (2010-2020年) 进行了研究.
- 收集的数据包括受孕方式 (自发,试管婴儿,ICSI),表现,出生方式,新生儿特征和母亲生殖史.
- 进行了统计分析,包括原始和调整的赔率比率,以评估关联.
主要成果:
- 2.7%的新生儿是通过ART怀孕的,4.4%的新生儿是通过部呈现分娩的.
- 部表现发生在7.6%的ART怀孕婴儿和4.3%的自发怀孕婴儿 (P=0.019).
- ART显示原始风险增加 (OR=1.67),但在调整为母亲年龄,平价和其他因素后,这种关联并不显着. 较高的母亲年龄和较低的平价与部呈现有显著的关联.
结论:
- 在ART怀孕中观察到的部呈现的风险增加可能与孕产妇的因素有关,主要是孕产妇的晚年和较低的平价.
- ART治疗本身可能不是部表现的独立风险因素.
- 未来的研究应该在评估ART结果时考虑这些混的母性特征.
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