Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Physiological Barriers01:25

Physiological Barriers

3.5K
Physiological barriers are semi-permeable cellular structures restricting drug diffusion into intracellular compartments and tissues. There are six types of physiological barriers: blood endothelial, cell membrane, blood-brain, blood-cerebrospinal fluid (CSF), blood-placenta, and blood-testis barriers.
The blood endothelial barrier is the most porous of these. It allows all small ionized, un-ionized, and lipophilic molecules to pass through the endothelial lining into the interstitial space...
3.5K
Barriers to Effective Communication II01:21

Barriers to Effective Communication II

3.6K
The barriers to effective communication also include cultural barriers, semantic barriers, gender barriers, and time constraints.
Cultural barriers:
Differences in values, beliefs, religion, knowledge, and tradition can significantly impact communication. Awareness of nonverbal cues is critical, especially when conversing with a patient from a different culture. What appears appropriate in one culture may be inappropriate in another.
Semantic barriers:
As a result of their tendency to use...
3.6K
Barriers to Effective Communication I01:30

Barriers to Effective Communication I

8.8K
A communication barrier is any distortion or interruption during a conversation, resulting in miscommunication of the message. A good communicator should know these barriers and continuously check for the listener's understanding by obtaining feedback.
Communication barriers include the following:
Physiological barriers: They are limitations caused by a person's health condition or disability, such as hearing loss, poor eyesight, illness, or unconsciousness. An example to overcome this...
8.8K
Surface Membrane Barriers01:18

Surface Membrane Barriers

1.1K
The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
1.1K
Masonry Curtain Walls01:20

Masonry Curtain Walls

1.1K
Masonry curtain walls employ brick or stone veneers supported by the building's structure to form an external cladding system that is both aesthetically appealing and functional. These walls are erected through two principal techniques, first by traditional layering of masonry units and second by using prefabricated panels. Traditional construction relies on steel shelf angles attached to the spandrel beam for support, with high-bond mortars ensuring secure attachment of masonry veneer...
1.1K
Composite Masonry Walls01:18

Composite Masonry Walls

1.2K
Composite masonry walls combine multiple wythes of the same or different masonry materials to create a unified structure. These walls feature wythes that are bonded together either through mortar-filled collar joints, grouted spaces, or more commonly, with rigid metal ties and reinforcements, with the use of masonry header units being rare. Metal ties are preferred because they effectively minimize water penetration, as these walls primarily absorb moisture and then release it into the...
1.2K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Phosphoproteomics in Vascular Biology and Disease: Illuminating Signaling in the Vessel.

Arteriosclerosis, thrombosis, and vascular biology·2026
Same author

Bmal1 Regulates Vascular Calcification via Noncanonical Circadian Pathway-Brief Report.

Arteriosclerosis, thrombosis, and vascular biology·2026
Same author

MED1 Regulates BMP/TGF-β in Endothelium: Implication for Pulmonary Hypertension.

Circulation research·2022
Same author

RNA Sequencing Reveals Beneficial Effects of Atorvastatin on Endothelial Cells in Acute Kawasaki Disease.

Journal of the American Heart Association·2022
Same author

Gout-induced endothelial impairment: The role of SREBP2 transactivation of YAP.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2021

相关实验视频

Updated: Jun 29, 2025

Author Spotlight: Applications of TEER Detection to Assess Cell Barrier Integrity
09:03

Author Spotlight: Applications of TEER Detection to Assess Cell Barrier Integrity

Published on: September 29, 2023

3.2K

这不仅仅是一个简单的障碍.

Erandi Velazquez-Miranda1, Ming He2

  • 1Department of Pathology, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, United States.

eLife
|March 27, 2024
PubMed
概括

内皮细胞亚群具有不同的基因表达,表观遗传和功能特征. 了解这些独特的形状对于推进血管生物学和疾病研究至关重要.

科学领域:

  • 血管生物学 血管生物学
  • 细胞和分子医学是细胞和分子医学.

背景情况:

  • 内皮细胞形成血管的内壁.
  • 在内皮细胞种群中存在异质性.
  • 独特的分子和功能特征定义了内皮细胞亚群.

研究的目的:

  • 阐明内皮细胞亚群的独特分子特征.
  • 描述不同内皮细胞类型的表观遗传变异.
  • 为了将基因表达和表观遗传特征与功能性质相关联.

主要方法:

  • 单细胞RNA测序用于分析基因表达.
  • 表观遗传特征分析技术 (例如,ATAC-seq,ChIP-seq).
  • 功能性测试用于评估细胞行为.

主要成果:

  • 基于转录基因数据的新型内皮细胞亚群的识别.
  • 与特定的内皮细胞功能相关的差异性表观遗传修饰.
  • 基因表达模式和不同的功能表型之间的相关性.

结论:

  • 内皮细胞异质性是由独特的基因表达和表观遗传景观驱动的.
关键词:
在 ERG ERG 里面,有很多东西可以做.动脉样硬化 动脉样硬化染色体是一种染色体.它们是内皮细胞的内皮细胞.表观遗传学是指表观遗传学.基因表达的基因表达方式遗传学 遗传学 遗传学 是一个基因组学就是基因组学.人类 人类 人类 人类 人类 人类 人类这是一种炎症炎症炎症炎症.血管生物学 血管生物学

更多相关视频

Models and Methods to Evaluate Transport of Drug Delivery Systems Across Cellular Barriers
18:57

Models and Methods to Evaluate Transport of Drug Delivery Systems Across Cellular Barriers

Published on: October 17, 2013

46.4K
Author Spotlight: Developing a Unique Modular Microphysiological System to Mimic Human Barrier Tissue
06:20

Author Spotlight: Developing a Unique Modular Microphysiological System to Mimic Human Barrier Tissue

Published on: February 16, 2024

1.0K

相关实验视频

Last Updated: Jun 29, 2025

Author Spotlight: Applications of TEER Detection to Assess Cell Barrier Integrity
09:03

Author Spotlight: Applications of TEER Detection to Assess Cell Barrier Integrity

Published on: September 29, 2023

3.2K
Models and Methods to Evaluate Transport of Drug Delivery Systems Across Cellular Barriers
18:57

Models and Methods to Evaluate Transport of Drug Delivery Systems Across Cellular Barriers

Published on: October 17, 2013

46.4K
Author Spotlight: Developing a Unique Modular Microphysiological System to Mimic Human Barrier Tissue
06:20

Author Spotlight: Developing a Unique Modular Microphysiological System to Mimic Human Barrier Tissue

Published on: February 16, 2024

1.0K
  • 这些分子差异是专门的内皮细胞功能的基础.
  • 对这些子群体的进一步研究可能会揭示血管疾病的新治疗点.