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Updated: Jun 29, 2025

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甲状腺功能障碍和自身免疫性甲状腺炎的维生素E摄入量和患病率:NHANES数据的横截面分析
Siying Liu1, Cihang Lu1, Liang He2
1Department of Endocrinology and Metabolism and the Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, People's Republic of China.
概括
较高的饮食维生素E摄入量与减少亚临床甲状腺功能低下和自身免疫性甲状腺炎有关,特别是在男性中. 这项研究强调了维生素E.
科学领域:
- 内分泌学 在内分泌学.
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 甲状腺疾病受到饮食因素的影响.
- 维生素E是一种具有抗氧化特性的必需营养素.
- 了解营养素与甲状腺之间的关系对于公共健康至关重要.
研究的目的:
- 为了检查饮食维生素E摄入量与甲状腺功能障碍之间的关联.
- 调查维生素E摄入量与甲状腺抗体阳性之间的联系.
- 通过使用国家调查数据,在大量成年人群中分析这些关系.
主要方法:
- 分析国家健康和营养检查调查 (NHANES) 数据 (2007-2012).
- 包括7773名没有怀孕的成年人,他们拥有完整的甲状腺和维生素E数据.
- 将维生素E摄入量分类为三级,并使用加权后勤回归和受限立方线.
主要成果:
- 随着维生素E摄入量增加,亚临床甲状腺功能障碍 (SCH) 患病率的下降趋势被观察到 (P-趋势=0.013).
- 较高的维生素E摄入量与一般人群中较低的SCH患病率显著相关 (OR = 0.28).
- 男性显示出更明显的保护作用,中等到高的维生素E摄入量与较低的SCH和自身免疫甲状腺炎 (AIT) 患病率有关.
结论:
- 饮食中增加的维生素E摄入量与亚临床甲状腺功能低下的患病率降低有关.
- 更高的维生素E摄入量可能会对自身免疫性甲状腺炎产生保护作用,特别是在男性中.
- 进一步的研究可能会阐明维生素E在甲状腺健康中的作用背后的具体机制.
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