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评估多发性硬化症的认知运动干扰:一种基于技术的方法

Jessica Podda1, Ludovico Pedullà1, Giampaolo Brichetto1,2

  • 1Scientific Research Area, Italian Multiple Sclerosis Foundation, 16149 Genoa, Italy.

Bioengineering (Basel, Switzerland)
|March 27, 2024
PubMed
概括
此摘要是机器生成的。

患有多发性硬化症的人经历认知运动干扰. 可穿戴式传感器和移动应用程序可以有效地测量双重任务成本,有助于对这些损伤的临床评估.

关键词:
认知障碍是一种认知障碍.认知-运动干扰干扰.这是一个双重任务.双重任务的成本是双重任务.多发性硬化症多发性硬化症语义流性的语义流性一个单一的任务.可以穿戴的可穿戴设备.

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科学领域:

  • 神经学 神经学
  • 康复技术 康复技术 康复技术
  • 生物医学工程 生物医学工程

背景情况:

  • 多发性硬化症 (MS) 常常导致结合的认知和运动缺陷.
  • 这些缺陷可能会损害执行双重任务 (DT) 的能力.
  • 评估认知运动干扰 (CMI) 对于管理MS至关重要.

研究的目的:

  • 确定基于新技术的参数,用于评估MS患者的CMI (PwMS).
  • 使用可穿戴技术来定义双重任务成本 (DTC) 的措施.
  • 评估内和移动应用程序对CMI评估的有用性.

主要方法:

  • 参与者执行了认知单任务 (ST),运动ST (行走) 和DT (组合任务).
  • 从口头流利任务中计算单词数和从内中计算步数.
  • 运动和认知DTC的计算是基于DT期间的性能变化.

主要成果:

  • 步数与ST和DT的走路距离有很强的相关性 (r=0.88-0.91,p<0.05).
  • 在DT期间,运动性能显著下降,而认知性能显示出文字输出逐渐下降.
  • 认知任务优先级可能解释观察到的性能变化.

结论:

  • 低成本的可穿戴设备可以在临床环境中有效评估CMI.
  • 这些工具有助于在PwMS中检测生态有效的DT损害.
  • 基于技术的评估为管理MS相关的功能限制提供了一种实际方法.