急性和慢性周围假肢关节感染之间的早期结果差异-一项回顾性单中心研究
Yasmin Youssef1, Elisabeth Roschke1, Nadine Dietze2
1Department of Orthopedics, Traumatology and Plastic Surgery, University Hospital Leipzig, Liebigstraße 20, 04103 Leipzig, Germany.
Antibiotics (Basel, Switzerland)
|March 27, 2024
概括
周围假肢关节感染 (PJI) 根据类型呈现不同. 急性晚期感染 (ALI) 显示出更糟糕的结果,需要比早期 (EI) 或慢性感染 (CI) 更密切的监测.
科学领域:
- 整形外科 整形外科 整形外科
- 传染性疾病 传染性疾病
- 临床结果研究研究
背景情况:
- 周围假肢关节感染 (PJI) 是关节整形术后的重大并发症,导致严重的发病率和死亡率.
- 了解不同PJI分类的不同结果对于有效的患者管理至关重要.
研究的目的:
- 评估和比较各种周围假肢关节感染实体的早期临床结果.
- 确定与不同类型的PJI相关的特定患者特征和风险因素.
主要方法:
- 一项回顾性,单中心研究分析了2018年至2019年期间为PJI治疗的115名患者.
- 患者被分为早期感染 (EI),急性晚期感染 (ALI) 和慢性感染 (CI) 组.
- 治疗后12个月评估结果,重点关注死亡率,无复发存活率 (RFS) 和术后并发症.
主要成果:
- 急性晚期感染 (ALI) 组表现为老年患者,较高的ASA得分,手术前CRP升高,以及衰竭和败血症的发病率增加.
- 与EI和CI相比,ALI患者的室内死亡率 (21.1%) 和ICU入院率 (50.0%) 的趋势较高.
- 在12个月后,EI的复发率为15.4%,ALI为38.1%,CI为36.4%,这表明ALI和CI的复发率明显更高.
结论:
- 在PJI实体之间,患者特征和早期结果存在明显的差异.
- 早期感染 (EI) 显示出更好的早期临床结果.
- 与EI和CI相比,急性晚期感染 (ALI) 需要在随访期间提高警,因为复发和术后并发症的风险较高.
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