性内炎:临床特征,病原体和影响视觉结果的因素
Xiaoxia Li1, Zhi Chen2,3,4,5, Xiuwen Zhang1
1Department of Pharmacy, Eye & ENT Hospital, Fudan University, Shanghai 200031, China.
Antibiotics (Basel, Switzerland)
|March 27, 2024
概括
性内炎 (FE) 通常是由创伤引起的,阿斯伯吉洛菌是常见的. 早期诊断和治疗,包括玻璃切除术和抗真菌注射,改善视觉结果,特别是当不由Aspergillus引起时.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 性内炎 (FE) 对视力构成重大威胁,创伤是主要原因.
- 了解微生物谱和风险因素对于有效管理至关重要.
研究的目的:
- 调查病因学,微生物谱和与真菌内耳炎 (FE) 视觉结果相关的危险因素.
- 为了确定预测FE患者更好的视觉预后的因素.
主要方法:
- 回顾性,单中心病例系列分析来自92名FE患者的102只眼睛.
- 分析了临床特征,病因,微生物学数据,管理和视觉结果.
- 后勤回归确定了与视觉结果相关的因素.
主要成果:
- 创伤是最常见的病因 (56.5%),还有Aspergillus spp. 占主导的物种 (33.3%).
- 帕斯普拉纳玻璃切除术和内抗真菌剂是常见的初始治疗方法.
- 只有34.3%的人获得了20/400或更好的最终最佳校正视敏度 (BCVA);更好的结果的因素包括初始BCVA>指数计数,角膜透的缺失和Candida感染.
结论:
- 早期诊断和及时治疗 (内腔切除术,内腔抗真菌药物) 可以减轻FE的严重视力损失.
- 有利的预后因素包括没有阿斯伯吉路斯感染,初始BCVA不比指数更糟糕,并且没有角膜干扰.
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