后冠状病毒疾病2019年大流行 抗菌耐药性
Lucia Boccabella1, Elena Gialluca Palma2, Ludovico Abenavoli3
1Internal Medicine Unit, Madonna del Soccorso General Hospital, Via Luciano Manara 7, 63074 San Benedetto del Tronto, Italy.
Antibiotics (Basel, Switzerland)
|March 27, 2024
概括
在COVID-19大流行期间和之后,抗菌素耐药性 (AMR) 在全球范围内显著增加,影响了细菌和真菌. 一个协调的全球方法和合理的抗菌药物使用对于打击这种日益增长的公共卫生威胁至关重要.
科学领域:
- 医学微生物学 医学微生物学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 抗菌素耐药性 (AMR) 是一个持续的全球健康挑战,COVID-19大流行加剧了这一挑战.
- 疫情导致抗微生物药物的使用增加,传播动态发生变化,影响AMR模式.
研究的目的:
- 在后COVID-19时代审查和综合有关AMR的定义和病原体的证据.
- 了解大流行对抗菌素耐药性的演变和特征的影响.
主要方法:
- 在PubMed和Medline进行了全面的文献搜索.
- 关键词包括"抗生素"",抗微生物耐药性"",SARS-CoV2"",COVID-19大流行"和"个人防护设备".
- 包括原创文章,评论,元分析和案例系列.
主要成果:
- 在全球范围内,AMR发生率在医院和门诊环境中显著上升 (5-50%),影响细菌和真菌.
- 疫情期间抗生素的使用增加和全球旅行后封锁促进了耐药生物体的传播.
- 在COVID-19感染本身和大流行后期AMR变化之间没有明确的直接关联.
结论:
- 在COVID-19大流行期间和之后,AMR显著增加和演变.
- 一个综合的,超国家级的监测系统对于管理AMR至关重要.
- 必须合理,个性化和规范地使用抗微生物药物.
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