左心室透支功能障碍与内血管血栓切除术后的功能不良结果有关
Tony Y W Li1, Emma M S Toh2, Ying Ying Koh2
1Department of Cardiology, National University Heart Centre Singapore, 1E Kent Ridge Road, NUHS Tower Block Level 9, Singapore 119228, Singapore.
Journal of cardiovascular development and disease
|March 27, 2024
概括
左心室扩张功能障碍 (LVDD) 与急性缺血性中风患者经历内血管血栓切除术 (ET) 的功能恢复恶化有关. 在这项研究中,LVDD没有显著影响住院死亡率. 建议进行进一步的研究.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 脑卒中医学 脑卒中医学
背景情况:
- 内血管血栓切除术 (ET) 改善了急性缺血性中风 (AIS) 与大血管封闭 (LVO) 的结果.
- 左心室扩张性功能障碍 (LVDD) 与其他心血管疾病的预后不佳有关.
- LVDD对中风后功能恢复的影响尚不清楚.
研究的目的:
- 调查LVO AIS患者接受ET的LVDD和临床结果之间的关系.
- 评估LVDD与短期死亡率和功能恢复的关联.
主要方法:
- 对261名接受ET的LVO AIS患者进行了回顾性队列研究.
- 3个月后LVDD与住院死亡率和修改的兰金尺度 (mRS) 分数 (0-2为良好的康复) 的相关性.
主要成果:
- 在31.4%的患者中存在LVDD.
- 在3个月后,LVDD与功能恢复较差有关 (OR 2.18,95% CI 1.04-4.54,p=0.038).
- 在调整后,LVDD与住院死亡率的增加没有显著关联 (OR 2.18,95% CI 0.60-7.99,p=0.240).
结论:
- 在接受LVO AIS的ET患者中,LVDD可能表明患者的治疗结果较差,超出了传统的心声回声测量措施.
- 进一步调查LVDD在中风恢复中的作用是有必要的.
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