目前对肠球菌内心炎的了解:一种隐藏在卫生保健提供者的眼前的疾病
1Department of Cardiac Surgery, Centre Cardiologique du Nord, 93200 Saint-Denis, France.
Pathogens (Basel, Switzerland)
|March 27, 2024
概括
菌可以直接殖民于未受损的血管表面,形成可能导致内心炎的生物膜. 这挑战了以前关于先前存在的组织损伤对于感染是必要的假设.
科学领域:
- 微生物学 微生物学
- 病变的发生和发病.
- 细菌生物膜是一种细菌生物膜.
背景情况:
- 菌 (Enterococcus faecalis) 是一种机会性病原体,与各种感染有关.
- 生物膜的形成对E. faecalis殖民和在胃肠道中的持久性至关重要.
- 内心炎传统上需要先前存在的内心损伤,通常是通过实验诱导的.
研究的目的:
- 审查关于E. faecalis内血管殖民的动物模型研究.
- 研究E. faecalis殖民无损内皮的能力.
- 检查完整的内皮表面上的生物膜形成.
主要方法:
- 历史和当代动物模型研究的审查.
- 对E. faecalis与内血管内皮表面相互作用的分析.
- 生物膜在不同宿主地点的形态比较.
主要成果:
- E. faecalis可以直接殖民于未受损的内血管内皮表面.
- 细菌形成了强大的微殖民地生物膜,包裹在细胞外基质中.
- 在胃肠表皮上观察到类似的生物膜表型.
结论:
- E. faecalis可以在完好无损的内皮上发起感染,挑战以前的观念.
- 在未受损的表面上形成生物薄膜是一个关键的毒性因素.
- 这些能力可能有助于无症状携带和传播感染,导致内心炎.
相关概念视频
Transmission-based Precautions I: Contact, Enteric, and Droplets
3.6K
Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
3.6K
Healthcare Associated Infections II: Preventive Measures
2.6K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.6K
Hand hygiene
3.2K
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Hand washing...
3.2K


