婴儿和儿童的 - - 一个叙述性的回顾
Anca Chiriac1,2,3, Adriana Diaconeasa4, Raluca Miulescu5
1Department of Dermatology, Nicolina Medical Center, Iasi, Romania.
European journal of pediatrics
|March 27, 2024
概括
是一种虫感染,影响全球3亿人,引起强烈的和潜在的细菌感染. 目前的治疗方法包括局部甲氨酸和口服甲氨酸,预计会有新的药物.
科学领域:
- 皮肤病学 皮肤病学
- 寄生虫学的寄生虫学
- 公共卫生 公共卫生
背景情况:
- 是一种广泛传播的外寄生虫感染,由*Sarcoptes scabiei* var.引起. 人类,影响全球大约3亿人.
- 婴儿和儿童最常受到影响,贫困和过度拥挤加剧了传播和治疗的挑战.
- 主要症状是剧烈的,导致睡眠障碍和脱皮,可能导致严重的细菌感染和死亡.
研究的目的:
- 审查目前对病流行病学,临床表现,诊断和治疗的理解.
- 突出导致治疗失败的因素和管理中的新出现的挑战.
- 提供目前正在开发的新型治疗剂的概述.
主要方法:
- 临床诊断仍然是主要的,支持皮肤镜检查进行非侵入性可视化.
- 皮肤片的显微镜是一种敏感的诊断工具,而聚合酶链反应 (PCR) 显示出可变的灵敏度和特异性.
- 审查当前的治疗指南和新兴的药理干预措施.
主要成果:
- 局部氨酸5%是推的第一线治疗方法,口服艾弗梅克丁仅用于耐药病例或广泛爆发.
- 治疗失败通常与应用不正确或未能治疗无症状家庭接触者有关.
- 随着COVID-19大流行和移民的增加,病发病率的增加也随之增加.
结论:
- 有效的病管理需要准确的诊断,适当的治疗应用,并解决社会环境因素.
- 遵守治疗方案和管理无症状携带者对于预防复发和耐药性至关重要.
- 目前正在进行的新型杀剂研究为未来改善治疗选择提供了希望.
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