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在老年人中不同痴呆症亚型中吞障碍的患病率:元分析
Alfiani Rahmi Putri1, Yu-Hao Chu2, Ruey Chen1,3,4
1School of Nursing, College of Nursing, Taipei Medical University, Taipei City 110, Taiwan.
Age and ageing
|March 27, 2024
概括
超过一半的老年痴呆症患者患有吞障碍. 这项研究强调了痴呆症亚型的流行率,有助于医疗保健专业人员识别老年人群中这种常见问题.
科学领域:
- 老年学是一门学科.
- 神经学 神经学
- 临床医学 临床医学
背景情况:
- 痴呆症的特征是蛋白质的异常积累,损害了对于吞至关重要的神经通路.
- 衰老加剧神经通路损伤,增加老年人食障碍的风险.
- 吞障碍 (吞障碍) 是痴呆症患者的一个重要并发症.
研究的目的:
- 为了确定不同类型痴呆症亚型中老年人食障碍的患病率.
- 提供关于不同类型痴呆症吞障碍频率的数据.
- 在老年痴呆症患者群体中为临床实践提供有关食障碍的信息.
主要方法:
- 在主要数据库 (PubMed,Embase,Scopus,Web of Science,OVID Medline) 进行了系统的文献搜索.
- 一项元分析使用了通用线性混合模型,并采用随机效应方法来收集流行数据.
- 研究质量是使用 Hoy 的标准来评估的,异质性是通过 Cochrane 的 Q,I2 统计数据和主持人分析来探索的.
主要成果:
- 分析了18项涉及12,532名患有痴呆症的老年人的研究.
- 在老年痴呆症患者中,吞障碍的总体综合患病率为58%.
- 患病率因痴呆症亚型而异:阿尔茨海默氏症痴呆症 (46.5%),帕金森氏症痴呆症 (34.9%),血管痴呆症 (18.8%),混合痴呆症 (16.3%),以及莱维体痴呆症 (12.2%).
- 阿尔茨海默氏症痴呆症的患病率最高 (58%的仪器评估,39%的临床评估).
- 导致异质性的因素包括病史,阿尔茨海默氏症痴呆症,痴呆症严重程度和特定的吞阶段障碍.
结论:
- 超过一半的老年痴呆症患者患有吞障碍.
- 调查结果为医疗保健专业人员提供了关键的见解,以识别老年痴呆症人口中缺食症.
- 早期识别和治疗吞障碍对于改善痴呆症护理患者的治疗结果至关重要.
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