Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Potential Due to a Polarized Object01:29

Potential Due to a Polarized Object

398
A neutral atom consists of a positively charged nucleus surrounded by a negatively charged electron cloud. When placed in an external electric field, the external electric force pulls the electrons and nucleus apart, opposite to the intrinsic attraction between the nucleus and the electrons. The opposing forces balance each other with a slight shift between the center of masses of the nucleus and the electron cloud, resulting in a polarized atom. On the other hand, a few molecules, like water,...
398
Propagation of Action Potentials01:23

Propagation of Action Potentials

5.7K
The propagation of an action potential refers to the process by which a nerve impulse, or "action potential," travels along a neuron.
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...
5.7K
Induced Electric Fields01:23

Induced Electric Fields

3.7K
The fact that emfs are induced in circuits implies that work is being done on the conduction electrons in the wires. What can possibly be the source of this work? We know that it’s neither a battery nor a magnetic field, as a battery does not have to be present in a circuit where current is induced, and magnetic fields never do any work on moving charges. The source of the work is in fact an electric field that is induced in the wires. For example, if a stationary conductor is placed in a...
3.7K
Mass Analyzers: Common Types01:19

Mass Analyzers: Common Types

604
The quadrupole mass analyzer consists of four cylindrical metal rods arranged in a diamond carrying a DC voltage and a radio-frequency AC voltage. The motion of ions through the quadrupole depends on the field strength, causing only ions of a certain m/z to resonate successfully and strike the detector at a given field strength. Though the transmission rate for these analyzers is high, the exact elemental composition of the sample is not determined because of low resolution; however, they are...
604
π Electron Effects on Chemical Shift: Overview01:27

π Electron Effects on Chemical Shift: Overview

1.1K
An applied magnetic field causes loosely bound π-electrons in organic molecules to circulate, producing a local or induced diamagnetic field over a large spatial volume. As the molecules tumble in solution, the field generated by π-electrons in spherical substituents results in a zero net field. However, the net field generated by π-electrons in non-spherical substituents is not zero. The effect of this induced field depends on the orientation of the molecule with respect to B0,...
1.1K
Induced Electric Dipoles01:28

Induced Electric Dipoles

4.2K
A permanent electric dipole orients itself along an external electric field. This rotation can be quantified by defining the potential energy because the external torque does work in rotating it. Then, the potential energy is minimum at the parallel configuration and maximum at the antiparallel configuration. While the former is a stable equilibrium, the latter is an unstable equilibrium.
Since the absolute value of potential energy holds no physical meaning, its zero value can be chosen as per...
4.2K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Efficient <sup>15</sup>N hyperpolarization of [<sup>15</sup>N<sub>3</sub>]metronidazole antibiotic via spin-relayed pulsed SABRE-SHEATH.

Journal of magnetic resonance open·2026
Same author

Angle-resolved Measurements Reveal the Origin of Signal Anisotropy in Pump-probe Microscopy.

bioRxiv : the preprint server for biology·2026
Same author

Investigation of <sup>15</sup>N-SABRE hyperpolarization at high pressures and in supercritical fluids.

Journal of magnetic resonance (San Diego, Calif. : 1997)·2025
Same author

Exchange-selective excitation pulses for dynamic magnetic resonance.

Science advances·2025
Same author

Alexander Pines and the end of an era.

Science advances·2025
Same author

The frontiers of chemical imaging.

Science advances·2024
Same journal

In This Issue.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Correction for Otsuki et al., Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Hive mind: Microbial communities and the making of memory.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Targets for disease modification in schizophrenia: New findings add to evidence for the involvement of the immune complement system.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Correction for Wang et al., The role of reduced aerosol masking from air pollutant emission reductions in recent global warming acceleration (2013-2023).

Proceedings of the National Academy of Sciences of the United States of America·2026
Same journal

Correction for Mishra, Ecology is not yet ready for AI-and why that matters.

Proceedings of the National Academy of Sciences of the United States of America·2026
查看所有相关文章

相关实验视频

Updated: Jun 29, 2025

Experimental Methods for Spin- and Angle-Resolved Photoemission Spectroscopy Combined with Polarization-Variable Laser
09:00

Experimental Methods for Spin- and Angle-Resolved Photoemission Spectroscopy Combined with Polarization-Variable Laser

Published on: June 28, 2018

9.9K

多轴场可以促进SABRE的超极化.

Jacob R Lindale1, Loren L Smith1, Mathew W Mammen2

  • 1Department of Chemistry, Duke University, Durham, NC 27708.

Proceedings of the National Academy of Sciences of the United States of America
|March 27, 2024
PubMed
概括
此摘要是机器生成的。

像反向交换信号放大 (SABRE) 这样的超极化方法可以增强NMR/MRI信号. 一种新的计算方法,MACHETE-SABRE,使用多轴脉冲来实现七倍的极化改进.

关键词:
过极化的超极化磁共振是一种磁共振.最好的控制和控制是最优的.

更多相关视频

Hyperpolarized Xenon for NMR and MRI Applications
16:20

Hyperpolarized Xenon for NMR and MRI Applications

Published on: September 6, 2012

19.6K
Author Spotlight: Non-Invasive Imaging of Complex Bio-Structures Using Polarization-Sensitive Two-Photon Microscopy
05:54

Author Spotlight: Non-Invasive Imaging of Complex Bio-Structures Using Polarization-Sensitive Two-Photon Microscopy

Published on: September 8, 2023

1.2K

相关实验视频

Last Updated: Jun 29, 2025

Experimental Methods for Spin- and Angle-Resolved Photoemission Spectroscopy Combined with Polarization-Variable Laser
09:00

Experimental Methods for Spin- and Angle-Resolved Photoemission Spectroscopy Combined with Polarization-Variable Laser

Published on: June 28, 2018

9.9K
Hyperpolarized Xenon for NMR and MRI Applications
16:20

Hyperpolarized Xenon for NMR and MRI Applications

Published on: September 6, 2012

19.6K
Author Spotlight: Non-Invasive Imaging of Complex Bio-Structures Using Polarization-Sensitive Two-Photon Microscopy
05:54

Author Spotlight: Non-Invasive Imaging of Complex Bio-Structures Using Polarization-Sensitive Two-Photon Microscopy

Published on: September 8, 2023

1.2K

科学领域:

  • 磁共振是一种磁共振.
  • 超极化技术 超极化技术
  • 计算化学计算化学

背景情况:

  • 低信号噪声比限制了NMR和MRI应用.
  • 超极化方法,如信号放大通过可逆交换 (SABRE),提供了显著的信号增强.
  • 当前的SABRE/X-SABRE方法虽然有效,但尚未达到理论极化极限.

研究的目的:

  • 探索新的方法来增强SABRE/X-SABRE中的两极分化.
  • 为了研究在低磁场中三维场调制的潜力.
  • 开发一种计算方法来优化SABRE中的极化转移.

主要方法:

  • 使用进化策略算法进行数值优化.
  • 为SABRE (MACHETE-SABRE) 方法开发了一种多轴计算机辅助的异质核转移增强.
  • 设计并测试了非直观的多轴脉冲序列.

主要成果:

  • 与连续激发相比,极化得到了七倍的改善.
  • 证明了MACHETE-SABRE在优化偏振转移方面的有效性.
  • 确定了新的,高效的多轴脉冲序列.

结论:

  • 马切特-萨布尔为显著增强NMR/MRI信号极化提供了一种新策略.
  • 开发的计算方法为克服传统SABRE方法的局限性提供了一条途径.
  • 通过先进的计算优化和脉冲序列设计,可以进一步改善超极化.