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Updated: Jun 29, 2025

Phenotypic and Functional Analysis of Activated Regulatory T Cells Isolated from Chronic Lymphocytic Choriomeningitis Virus-infected Mice
07:17

Phenotypic and Functional Analysis of Activated Regulatory T Cells Isolated from Chronic Lymphocytic Choriomeningitis Virus-infected Mice

Published on: June 22, 2016

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狼敏感性基因Pbx1通过Rtkn2表达控制调节性T细胞的发育,稳定性和功能

Seung-Chul Choi1, Yuk Pheel Park1, Tracoyia Roach1

  • 1Department of Microbiology, Immunology, and Molecular Genetics, University of Texas Health San Antonio, TX 78229-3900, USA.

Science advances
|March 27, 2024
PubMed
概括

前B细胞白血病转录因子1 (Pbx1) 对调节性T (Treg) 细胞稳定性至关重要. 降低Pbx1水平会损害Treg功能,加剧诸如狼之类的自身免疫性疾病.

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Expression of Exogenous Cytokine in Patient-derived Xenografts via Injection with a Cytokine-transduced Stromal Cell Line12:58

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