巴西间歇性肺部疾病的相对发病率
Simone Lobo Krupok Matias1, Carlos Alberto de Castro Pereira1, Maria Raquel Soares1
1Hospital São Paulo, Universidade Federal de São Paulo, São Paulo (SP) Brasil.
连接组织疾病相关的间歇性肺病 (ILD) 在巴西最常见,其次是过敏性肺炎 (HP). 对环境暴露的认识对于防止HP的预防至关重要.
科学领域:
- 肺部病理学 肺部病理学
- 类风湿病学 类风湿病学
- 流行病学 流行病学
背景情况:
- 间歇性肺病 (ILD) 代表了一组异质的呼吸系统疾病.
- 了解ILDs的流行病情景对于公共卫生倡议和临床管理至关重要.
研究的目的:
- 为了确定不同类型的事件间歇性肺病 (ILDs) 在巴西的相对频率.
- 为了解巴西人口中ILD的诊断模式和患病率提供见解.
主要方法:
- 从2013年1月到2020年1月,在巴西的六个推中心进行了回顾性调查.
- 诊断是根据国际标准或多学科讨论 (MDD) 建立的,无法分类的ILD是由缺乏特定诊断或数据不一致而定义的.
主要成果:
- 该研究分析了1,406名患者,结缔组织疾病相关的ILD (27%) 是最常见的诊断,其次是过敏性肺炎 (HP) (23%).
- 异形性肺纤维化 (14%),不可分类的ILD (10%) 和肉类瘤 (6%) 也是显著的诊断. 在参与中心中观察到诊断的显著差异.
- 关键发现包括高HRCT纤维化率 (74%) 和在33%的病例中检测到自身抗体.
结论:
- 连接组织疾病相关的ILD是巴西占主导地位的ILD,这强调了肺病学家和风湿病学家之间合作的必要性.
- 建议强调患者的抗原暴露史和公共卫生运动以减轻暴露风险,特别是HP预防.
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