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Updated: Jun 29, 2025

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对与疾病相关的内解体外核酶PLD3和PLD4的结构和机制见解

Meng Yuan1, Linghang Peng2, Deli Huang2

  • 1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.

Structure (London, England : 1993)
|March 27, 2024
PubMed
概括

脂酶D3和D4 (PLD3/4) 是与自身免疫性疾病相关的内酶. 结构和生物化学研究揭示了它们的催化机制以及突变如何影响酶功能,为治疗设计提供了洞察力.

关键词:
PLD3 PLD3 在线学习PLD4 PLD4 在线阅读TLR信号传输系统的信号.晶体结构 晶体结构与疾病相关的突变.异核酶是外核酶的一种.

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