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Updated: Jul 19, 2026

Single-cell Profiling of Developing and Mature Retinal Neurons
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Single-cell Profiling of Developing and Mature Retinal Neurons

Published on: April 19, 2012

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单细胞概况转录显示细胞异质性和细胞交叉声在胆管新血管化模型中的细胞异质性和细胞交叉声

Ming Tong1, Yun Bai2, Xiaoyan Han1

  • 1Eye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, 200031, China.

Experimental eye research
|March 27, 2024
PubMed
概括

这项研究使用单细胞测序来识别视网膜色素上皮质/胆核复合体中的细胞类型,揭示了与与年龄相关的黄斑变性相关的胆核新血管化相关的特定内皮细胞,纤维细胞和巨细胞.

关键词:
与年龄相关的黄斑变性.冠状腺新血管化疗法内皮质异质性 内皮质异质性单细胞测序是一种单细胞测序.

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Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...
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Diversity in Cell Signaling Responses

The physiological function of a cell and cellular communication are outcomes of a range of extrinsic signals, intracellular signaling pathways, and cellular responses. No two cell types express the same repertoire of signaling components. Receptors are highly selective for their cognate ligands, but once activated, they can alter multiple cellular processes such as DNA transcription, protein synthesis, and metabolic activity. 
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