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靠近性胃切除术后长期体重减轻的危险因素:回顾性分析
Yuya Agatsuma1, Koki Nakanishi2, Chie Tanaka1
1Department of Gastroenterological Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Anticancer research
|March 27, 2024
概括
在近腹切除术 (PG) 后严重的体重减轻与早期脂肪量减少和缺乏恢复有关. 早期的营养干预可以预防胃癌PG患者的长期BWL.
科学领域:
- 胃肠病学 胃肠病学
- 手术瘤学手术瘤学
- 营养科学 营养科学
背景情况:
- 靠近胃切除术 (PG) 是一种治疗早期靠近胃癌的方法.
- 虽然PG可以保持食物储存并最大限度地减少体重减轻 (BWL),但显著的BWL可能会对患者的福祉和生存产生负面影响.
- 识别导致PG后BWL的因素对于改善患者的治疗结果至关重要.
研究的目的:
- 为了确定与近端胃切除术 (PG) 后的体重减轻 (BWL) 相关的因素.
- 分析患者特征,手术细节和与BWL相关的营养标记.
- 为了区分中度和严重群体之间的BWL模式.
主要方法:
- 对58名为胃或食管胃结癌接受PG治疗的患者进行了回顾性分析.
- 根据12个月的术后BWL,患者被分为BWL中度 (n=29) 和BWL严重 (n=29) 组.
- 两组之间的患者特征,手术数据和营养标志物的比较.
主要成果:
- 平均BWL为14.0±7.2%. 这是一个很好的结果.
- 严重的BWL组经历了显著的早期BWL (在1个月内) 主要来自体脂量减少,在60个月内没有恢复.
- 在24个月后,BWL-中度组显示逐渐恢复. 两组人都减少了更多的脂肪,而不是减少了肌肉. 在BWL严重的组中,血红蛋白水平没有恢复.
结论:
- 在PG之后的严重BWL的特点是显著的早期脂肪量减少,持续缺乏恢复.
- 适度的BWL显示了一种逐渐恢复的模式.
- 建议进行早期的术后营养干预,以减轻长期BWL,并改善PG患者的治疗结果.
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