NAP1L1通过E3泛酸酶UBR4调节BIRC2泛酸修饰,从而决定肝细胞癌的进展

Shi-Long Zhang1,2,3, Shen-Jie Zhang1,2, Lian Li4

  • 1Department of Hepatobiliary Surgery, The Affiliated Hospital of Guizhou Medical University, 550001, Guiyang, China.

Cell death discovery
|March 28, 2024
PubMed
概括

核细胞组合蛋白1-like 1 (NAP1L1) 通过控制Baculoviral IAP重复含有2 (BIRC2) 通过UBR4.4通过ubiquitination控制肝细胞癌 (HCC) 的进展. 抑制NAP1L1可以抑制HCC的扩散,并促进细胞亡.

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