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Updated: Jun 29, 2025

Utilizing Time-Resolved Protein-Induced Fluorescence Enhancement to Identify Stable Local Conformations One α-Synuclein Monomer at a Time
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Utilizing Time-Resolved Protein-Induced Fluorescence Enhancement to Identify Stable Local Conformations One α-Synuclein Monomer at a Time

Published on: May 30, 2021

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在同一α-synuclein位点的酸化和O-GlcNAcylation产生不同的纤维结构

Jinjian Hu1, Wencheng Xia2, Shuyi Zeng3,4

  • 1Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing, 100084, China.

Nature communications
|March 28, 2024
PubMed
概括

翻译后的修改,如酸化和O-GlcNAcylation在同一个网站的α-synuclein创建不同的粉样纤维结构. 这些经过修改的纤维素显示出减少的神经毒性,影响帕金森病的病理学.

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