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Updated: Jun 29, 2025

Isolation of Intermediate Filament Proteins from Multiple Mouse Tissues to Study Aging-associated Post-translational Modifications
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Isolation of Intermediate Filament Proteins from Multiple Mouse Tissues to Study Aging-associated Post-translational Modifications

Published on: May 18, 2017

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由METTL3介导的m6A修饰增加了hspa1a的稳定性,以抑制骨质细胞衰老

Yaobin Wang1,2,3, Yi Chen1,2,3, Hefang Xiao1,2,3

  • 1Department of Orthopaedics, Lanzhou University Second Hospital, Lanzhou, Gansu, 730030, China.

Cell death discovery
|March 28, 2024
PubMed
概括

甲基转移酶类3 (METTL3) 抑制骨质细胞衰老,这是老年骨质疏松症的关键因素. METTL3稳定了hspa1amRNA,为骨质疏松症提供了潜在的治疗点.

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