在患有急性淋巴细胞白血病的婴儿中PEGasparaginase的药理动力学

Leiah J Brigitha1,2, Veerle Mondelaers3, Yiwei Liu4

  • 1Princess Máxima Center for Pediatric Oncology, Heidelberglaan 25, 3584 CS, Utrecht, Netherlands.

PubMed
概括

患有急性淋巴细胞白血病 (ALL) 的婴儿中PEGasparaginase的药理动力学与年龄较大的儿童相似. 建议婴儿服用1,500 IU/m2的推剂量,并进行治疗药物监测以获得最佳治疗.

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