使用全球敏感性分析来评估弱基本化合物的口服吸收:二皮里达摩尔的一个案例

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Updated: Jun 29, 2025

An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment
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An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment

Published on: December 3, 2020

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Siddharth S Kesharwani1, Guillaume Louit2, Fady Ibrahim3

  • 1US Early Development Biopharmacy, Synthetics Platform, Sanofi, 350 Water St, Cambridge, MA, 02141, USA.

Pharmaceutical research
|March 28, 2024
PubMed
概括

全球系统分析 (GSA) 通过确定关键参数来改进口服吸收建模,从而更准确地预测药物度和暴露. 这种方法可以提高药物开发早期的决策能力.

关键词:
生物制药公司生物相关的媒体.二胺分子是什么意思口服吸收 口服吸收降水 降水 降水 降水 降水溶解度 溶解度 溶解度 溶解度

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