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Updated: Jun 29, 2025

Accelerated Type 1 Diabetes Induction in Mice by Adoptive Transfer of Diabetogenic CD4+ T Cells
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系统性免疫细胞失调和单细胞RNA-seq揭示的分子亚型的1型糖尿病患者

Mohammad Amin Honardoost1,2,3, Andreas Adinatha1, Florian Schmidt1

  • 1Laboratory of Systems Biology and Data Analytics, Genome Institute of Singapore (GIS), A*STAR (Agency for Science, Technology and Research), Singapore, 138672, Singapore.

Genome medicine
|March 28, 2024
PubMed
概括

1型糖尿病 (T1DM) 涉及显著的免疫细胞网络变化,影响基因表达和细胞功能. 这项研究确定了T1DM患者分层的分子亚型和潜在生物标志物.

关键词:
周围血液单核细胞 (PBMCs) 是一种细胞.单细胞RNA测序 (scRNA-seq) 是一种第1型糖尿病 (T1DM) 是一种糖尿病.

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