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生物制剂和儿童和青少年的健康:一个叙事审查
Evangelia Xenopoulou1, Ioanna Kontele1, Theodoros N Sergentanis1
1Laboratory of Epidemiology, Health Determinants and Well-Being, Department of Public Health Policy, University of West Attica, 115 21 Athens, Greece.
Children (Basel, Switzerland)
|March 28, 2024
概括
生物制剂在治疗各种儿童疾病,包括消化系统问题和感染方面表现有前途. 需要进一步的研究来确认益处,并解决儿童和青少年的局限性.
科学领域:
- 微生物学 微生物学
- 儿科 儿科 儿科
- 胃肠病学 胃肠病学
背景情况:
- 人们对肠道微生物群与健康的联系越来越感兴趣.
- 儿童和青少年具有独特的生理特征,影响健康.
- 生物制剂正在儿童群体中探索其潜在的健康益处.
研究的目的:
- 审查生物药在儿科条件中的作用和局限性.
- 综合生物学的证据,以解决常见的儿童健康问题.
主要方法:
- 在PubMed上发表的研究的叙述性综述,截至2023年10月.
- 专注于儿童和青少年的生物药物管理.
主要成果:
- 生物制剂在治疗和预防传染性腹,抗生素相关腹和死性肠球炎方面显示出潜在的益处.
- 在功能性胃肠道疾病 (婴儿结肠,功能性腹痛,刺激性肠综合征),H. pylori根除,性结肠炎,囊炎和亚托邦性皮肤炎预防方面观察到积极的结果.
- 在这个年龄组中发现与益生菌使用相关的局限性.
结论:
- 生物制剂可能对儿童和青少年的几种健康状况产生有益影响.
- 需要进一步进行高质量的随机对照试验,特别是针对青少年和年轻人.
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